BEGIN:VCALENDAR VERSION:2.0 PRODID:-//hacksw/handcal//NONSGML v1.0//EN CALSCALE:GREGORIAN BEGIN:VEVENT LOCATION:Moscow\, Ordzhonikidze St.\, 3 DESCRIPTION:Pyrrole core is the basis of many pharmacologically active compounds. For example\, 3-substituted pyrroles are found in a variety of medicinal and agrochemical applications\, such as efficient inhibitors of histone deacetylase\, HIV-1 transcriptase\, and COX-1/COX-2 cyclooxygenases. Furthermore\, the 4-acetyl pyrroles (JWH series) has moderate affinity for the CB1 receptor. Besides a wide range of applications in medicinal chemistry pyrroles are also found to be electronically polarizable and oxidizable building blocks for polymeric and supramolecular structures for applications in nonlinear optics. DTSTART:20190613T090000Z DTEND:20190613T150000Z SUMMARY:Iliy Efimov «Novel and convenient route toward 2\,4-disubstituted pyrroles based on the reaction of enaminones and isocyanides» URL;VALUE=URI:/media/events/iliy-efimov-novel-and-convenient-route-toward-24-disubstituted-pyrroles-based-on-the-reaction-of-enaminones-and-isocyanides/ DTSTAMP:20250502T101450Z UID:681470ea4b384 END:VEVENT END:VCALENDAR